منابع مشابه
Melatonin has multiorgan effects.
Melatonin, widely used to counter transatlantic travel jet lag and insomnia, is synthesized in the suprachiasmatic nucleus of the anterior pituitary gland. Its release into the circulation is stimulated by the onset of darkness, followed by a progressive decrease in blood levels with the onset of dawn. Melatonin administration can maintain the quality of sleep and help to counteract age-induced...
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Melatonin (N-acetyl-5-methoxytryptamine, MLT), the main hormone produced by the pineal gland, not only regulates circadian rhythm, but also has antioxidant, anti-ageing and immunomodulatory properties. MLT plays an important role in blood composition, medullary dynamics, platelet genesis, vessel endothelia, and in platelet aggregation, leukocyte formula regulation and hemoglobin synthesis. Its...
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A study found that patients taking the recommended 3-mg dose of the sleep aid eszopiclone (Lunesta) at bedtime continued to have impaired driving skills, memory, and coordination for as long as 11 hours after ingestion. Patients were often unaware they remained impaired. As a result, the FDA has recommended decreasing the starting dosage of eszopiclone to 1 mg at bedtime. The change should resu...
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*Corresponding author: Maryam Tavakoli M.D, Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. Email: [email protected] Melatonin is a hormone produced in the pineal gland. Melatonin is produced of tryptophan and serotonin and is metabolized to 6-hydroxyl melatonin in the liver (1-3). Melatonin is a highly important antioxidant. Free radicals damages cells...
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The gastrointestinal tract represents the most important extra pineal source of melatonin. Presence of melatonin (M) suggests that this hormone is somehow involved in digestive pathophysiology. Release of GI melatonin from serotonin-rich enterochromaffin EC cells of the GI mucosa suggest close antagonistic relationship with serotonin (S) and seem to be related to periodicity of food intake. Foo...
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ژورنال
عنوان ژورنال: European Heart Journal - Cardiovascular Pharmacotherapy
سال: 2016
ISSN: 2055-6837,2055-6845
DOI: 10.1093/ehjcvp/pvv037